Applied Laboratory Science & Operations (ASO)
This course provides the framework for DNA analysis. The subject is developed so as to provide the student with an enhanced understanding of DNA analysis, its collection, preservation, and processing. The principles and techniques of current methods of DNA analysis will be taught and discussed, and the interpretation of data generated through the analysis of DNA will be reviewed.
This course will provide students with an overview of advanced instrumentation in the life and chemical sciences. Students will first learn the theory behind each instrument and its potential uses. Students will then be involved in the planning of an experiment using each instrument. Finally that experiment will be run and its results analyzed and interpreted. Instrumentation will include: confocal microscopy, capillary electrophoresis, gas chromatography/mass spectrometry, and inductively coupled plasma optical emission spectrometry.
This course introduces students to principles and methods employed in toxicological assays. Principles in pharmacology and toxicology will be presented in the context of abused and toxic substances commonly encountered in forensic, clinical, and laboratory settings. The methods for collecting and analyzing substances such as hallucinogens, amphetamines, marijuana, cocaine, opioids, barbiturates, benzodiazepines, and alcohol will be discussed.
This course examines the professional code of ethics and the role of the life scientist in performing applied research endeavours. Standard code of conduct, as applied to laboratory science, will be explored as well as guidelines for professionalism, appropriate conduct, and what makes good as well as bad science.
This course provides students with the opportunity to explore the practical applications of managing an applied science laboratory. Topics such as budgeting, resource allocation, managing personnel, issues involving facilities and safety agency compliance, dealing with outside agencies, and other pertinent issues will be discussed.
Trace Analysis and Microscopy provides an in-depth examination of the proper collection, preservation, identification and comparison of items such as hair, paint, glass, fibers, and soil and the techniques used to analyze these types of trace evidence. The theory and practical application of various types of microscopy methodologies used in trace analysis are discussed.
This course combines the latest techniques in DNA analysis including mitochondrial DNA sequencing, YSTR typing, and sequence homology analysis with statistical principles used for the specific tests as well as for research and validation projects. Additional subjects may include low-copy number analysis and degraded sample interpretation.
In small groups, students will select a research interest, perform a thorough background literature review in that area, devise a research project, formulate a hyopthesis and draft a well-controlled experimental design. Students will then conduct their research project and gather relevant data under the supervision of a faculty research coordinator.
Under the guidance of their faculty research coordinator, students will analyze the data generated in ASO670 and interpret its meaning. Students will then draft their research thesis and seminar presentation. This course concludes with a public defense of that thesis and its submission to the University.